Blar i forfatter "Hira, Jonathan"

Viser treff 1-4 av 4

    • Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress 

      Petrovic, Voin; Nepal, Anala; Olaisen, Camilla; Bachke, Siri; Hira, Jonathan; Søgaard, Caroline Krogh; Røst, Lisa Marie; Misund, Kristine; Andreassen, Trygve; Melø, Torun Margareta; Bartosova, Zdenka; Bruheim, Per; Otterlei, Marit (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-05)
      The use of garlic and garlic-based extracts has been linked to decreased incidence of cancer in epidemiological studies. Here we examine the molecular and cellular activities of a simple homemade ethanol-based garlic extract (GE). We show that GE inhibits growth of several different cancer cells in vitro, as well as cancer growth in vivo in a syngeneic orthotopic breast cancer model. Multiple myeloma ...

    • Autofluorescence mediated red spherulocyte sorting provides insights into the source of spinochromes in sea urchins 

      Hira, Jonathan; Wolfson, Deanna; Andersen, Aaron John Christian; Haug, Tor; Stensvåg, Klara (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-24)
      Red spherule cells (RSCs) are considered one of the prime immune cells of sea urchins, but their detailed biological role during immune responses is not well elucidated. Lack of pure populations accounts for one of the major challenges of studying these cells. In this study, we have demonstrated that live RSCs exhibit strong, multi-colour autofluorescence distinct from other coelomocytes, and with ...

    • Evidence for association of Vibrio echinoideorum with tissue necrosis on test of the green sea urchin Strongylocentrotus droebachiensis 

      Hira, Jonathan; Stensvåg, Klara (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-22)
      “Sea urchin lesion syndrome” is known as sea urchin disease with the progressive development of necrotic epidermal tissue and loss of external organs, including appendages on the outer body surface. Recently, a novel strain, Vibrio echinoideorum has been isolated from the lesion of green sea urchin (Strongylocentrotus droebachiensis), an economically important mariculture species in Norway. V. ...

    • From Differential Stains to Next Generation Physiology: Chemical Probes to Visualize Bacterial Cell Structure and Physiology 

      Hira, Jonathan; Uddin, Md Jalal; Haugland, Marius Myreng; Lentz, Christian Stephan (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-26)
      Chemical probes have been instrumental in microbiology since its birth as a discipline in the 19th century when chemical dyes were used to visualize structural features of bacterial cells for the first time. In this review article we will illustrate the evolving design of chemical probes in modern chemical biology and their diverse applications in bacterial imaging and phenotypic analysis. We will ...